XL CCND1
The XL CCND1 probe is designed as a break apart probe. Its orange labeled part hybridizes proximal to CCND1 (BCL1) and the MYEOV gene at 11q13; the green labeled probe hybridizes to the distal region of CCND1.
The t(11;14)(q13;q32) chromosomal translocation is the hallmark of mantle cell lymphoma (MCL) and is found in approximately 30 % of multiple myeloma (MM) tumors with a 14q32 translocation. Variant translocations can fuse CCND1 also with other genes, such as IGK or IGL.
Cena za kus: pro registrované
The t(11;14)(q13;q32) chromosomal translocation is the hallmark of mantle cell lymphoma (MCL) and is found in approximately 30 % of multiple myeloma (MM) tumors with a 14q32 translocation. Variant translocations can fuse CCND1 also with other genes, such as IGK or IGL.
Cena za kus: pro registrované
